Steroid Induced Diabetes
Corticosteroids are used to reduce harmful inflammation but can lead to diabetes – often referred to as steroid diabetes.
People on steroids who are already at a higher risk of type 2 diabetes or those who need to take steroids for longer periods of time are the most susceptible to developing steroid-induced diabetes.
WHAT IS THE ROLE OF STEROIDS?
Steroids are taken to reduce inflammation, brought on by the body’s immune system, and can be taken as treatment for a number of illnesses including:
- Rheumatoid arthritis
- Crohn’s disease
- Ulcerative colitis
To achieve their purpose, corticosteroids mimic the action of cortisol, a hormone produced by the kidneys and responsible for bringing on our body’s classic stress response of higher blood pressure and increased blood glucose levels.
Corticosteroids increase insulin resistance thus allowing blood glucose levels to rise and remain higher.
WHAT ARE THE SYMPTOMS OF STEROID INDUCED DIABETES?
High blood glucose levels whilst taking steroids may subside after you stop taking steroids, however, some people may develop type 2 diabetes which will need to be managed for life.
Type 2 diabetes is more likely to develop following longer-term usage of steroids, such as usage of oral corticosteroids for longer than 3 months.
AM I AT RISK OF DEVELOPING STEROID INDUCED TYPE 2 DIABETES?
People at a higher risk of developing type 2 diabetes include:
- Those that are overweight
- If you have one or more close family members with type 2 diabetes
- If you have had gestational diabetes
- If you have polycystic ovary syndrome
- If you are over 40 and of Caucasian origin
- If you are over 25 and are of South Asian, African-Caribbean or Middle Eastern origin
DID STEROIDS BRING ON MY TYPE 2 DIABETES?
There has been debate as to whether corticosteroids are a cause for diabetes or whether steroids advance the development of existing type 2 diabetes.
A study published in 2012, carried out by the University of Sydney, looked to investigate answers to the question.
The study, titled Steroid-Induced Diabetes: Is It Just Unmasking of Type 2 Diabetes? found that those which developed new-onset steroid-induced diabetes had lower risk profiles than is typical of people with type 2 diabetes.